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The e-cigarette has been available in the UK from 2005 - albeit early generation devices that are obsolete by todays standards - and the decline in youth smokers from 2006 to 2018 was from 20% down to 5% - so in the time that e-cigarettes have been available, the youth smoking rates in the UK have continued to decline

250 M tert -butyl H 2 O 2 (TBHP, Sigma Aldrich) treatment was used as a positive control

The sale of heat-not-burn products should remain banned in Australia

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